Content Library: The Binding Brief

(All the useful information under one umbrella)

On this page, you’ll find our entire library of contents from my weekly newsletter The Binding Brief. The content is split into different categories based on the sections of my newsletter. So that, YOU can quickly navigate to the section and topics that interest you the most!

1. Raw Data: All the raw unfiltered thoughts and conversations from me

2. This Week’s Deep Dive: The long-form informative content on antibodies

3. Bench Notes: Tips and tricks for lab experiments

4. Antibody Spotlight: The antibody of the week and why it was important

5. In Silico: Antibody development in the AI world

6. Antibody Terms: Commonly used terminology

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1. Raw Data

• Does it matter what you work on (or) who you work with?

• Is it alright to rest and not be productive?

• Does someone’s success take away from us?

• What’s the real role of scientists in this AI world?

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2. This Week’s Deep Dive

• Antibodies and their elegant structure

• Antibodies: How are they named?

• 10 tips for navigating lab meetings

• How do you choose a PhD research topic?

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3. Bench Notes

• Leakproof your SDS-PAGE gels in the lab

• Benchling: Integrate your molecular biology suite and lab notebook into one

• Calculating accurate protein concentrations using a NanoDrop spectrophotometer

• CamSol: To predict protein solubility score

• Ellman’s Assay: A quick way to check disulfide bond formation in your proteins

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4. Antibody Spotlight

• Inmazeb (REGN-EB3) and Ebanga (mAb114): Will they work against the 2026 Ebola outbreak in DRC and Uganda?

• MBP134: An experimental Ebola drug for the Bundibugyo virus

• ❗️p53 Antibodies by Thermo Fisher Scientific

• ❗️Antibodies used against p16^INK4a or p16-ARC?

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5. In Silico

• How does DeepMind decide which problems to solve: Interview with Pushmeet Kohli (VP, Science and Strategic Initiatives at Google DeepMind)

• Nature publishes 3 AI papers on the same day: Robin, Co-Scientist, and ERA

• CamSol: To predict protein solubility score

• Review article on de novo protein design?

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6. Antibody Terms

• Polyclonal versus Monoclonal Antibodies

• Affinity versus Avidity

• Epitope versus Paratope

• Native versus Recombinant Antibodies

Check out all the editions right here.